Updated and revised, this fourth edition of a bestseller provides current and comprehensive information on all aspects of drug design and discovery. The first part of the book covers general aspects, methods, and principles and the second section covers specific targets and diseases. Topics new to this edition include biostructure- and ligand-based drug design, natural products, imaging, neurotransmitter transporters, opioid and cannabinoid receptors, hypnotics, neglected diseases, and antibiotics. Each chapter includes references for further study. Most chapters also supply background and history needed to provide context, as well as conclusions that summarize the important points.
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Pharmacology
Medicinal & Pharmaceutical Chemistry
Textbook
Undergraduate

NO TE PIERDAS LAS ETAPAS DE CHRIS CLAREMONT Y JAMES ROBINSON EN WILDC.A.T.S.En este tercer tomo de ARCHIVOS WIlDStORM: WIlDC.A.t.S, HellC.A.t.S, encontrarás los números 10-19 de la serie original americana. En él descubriremos a una antigua y poderosa enemiga de Zealot; de la mano de Erik Larsen, los Cats conocerán a los Freak Force; veremos un enfrentamiento WildCats contra WildCats; y se prepara una peligrosa tormenta que se desatará en el próximo volumen: Wildstorm Rising.

1ª edición.

Este libro presenta un método global e integral para la salud de sus pies.
Con él aprenderá a identificar la causa de su dolor y podrá mejorar el pronóstico de sus dolencias. Para ello le enseña cómo introducir algunos cambios en su vida que mejorarán la salud de sus pies y a incorporar el programa básico de ejercicios del método Spiraldynamik®. Así conseguirá mejorar la percepción y la movilidad al tiempo que estimulará el fortalecimiento y la coordinación.
También encontrará programas de ejercicios para problemas específicos: pie valgo, pie plano transverso, hallux valgus, espolón calcáneo, dedos en garra, etc.
El Dr. Christian Larsen, médico y director del Institut für Spiraldynamik® en la clínica privada Bethanien, en Zúrich, es investigador, autor, docente y cofundador del método Spiraldynamik®.

The proceedings of the 11th International Conference and Field trip on Landslides deal with landslides in soil and rock as well as snow and slush avalanches, and contain contributions from 18 countries.
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Georisk & Hazards
Hazards & Disasters
Proceedings

Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery. The book follows drug design from the initial structure-activity relationship to the final processes of clinical evaluation and registration. It covers the design of drugs for particular cellular targets such as ion channels and receptors and examines specific classes of drugs such as peptidomimetics, antivirals and anticancer agents. Also included is coverage of gene technology in pharmaceutical research, computer modelling techniques, and combinatorial approaches.
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Pharmacology
Textbook
Undergraduate

The rapid development of different aspects of glutamate and GABA receptor research makes it difficult to establish a general view of the field. Studies of the receptors are a multi-disciplinary task employing many specialised techniques. Glutamate and GABA Receptors and Transporters: Structure, Function and Pharmacology conveys recent discoveries in a framework of the basic concepts in the field of glutamate and GABA receptor research. Suitable for postgraduate students, it is also beneficial for industrial and academic research scientists in both the glutamate and GABA field, as well as universities offering programs in neuroscience, molecular pharmacology or medicinal chemistry.
• Pharmaceutical Science Series
Neuroscience
Pharmacology
Medicinal & Pharmaceutical Chemistry
Reference
Professional