Epigenetic changes are essential to normal development, but these changes can also cause problems including the disabling of genes that suppress tumors. At present more than a dozen drugs that target epigenetic changes are in clinical trials. Epigenetics in Biology and Medicine offers a comprehensive overview of epigenetics, both in normal functions and disease states. This book presents contributions from international experts, addressing both theoretical and methodological issues. It discusses cell biology and the role of epigenetics in human, animal, and plant diseases. The text also covers DNA methylation inhibitors, histone modifications, and epigenomics, as well as the impact that diet has on epigenetic changes.
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Cell Biology
Genetics
Molecular Biology
Reference
Professional

An invaluable handbook for researchers and clinicians. Written by leaders in the field, this exceptional compilation of articles outlines the best techniques to use when addressing questions concerning the cytosine methylation status of genomic DNA.
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Molecular Biology
Genetics
Oncology
Reference
Professional