Microfluidics-based biochips combine electronics with biochemistry for newly emerging application areas such as point-of-care medical diagnostics, on-chip DNA analysis, automated drug discovery, and protein crystallization. This book envisions an automated design flow for microfluidic biochips. It offers newly designed automation solutions for problems unique to digital microfluidics. The authors provide a comprehensive methodology for the automated design, test, and use of robust and low-cost manufactured digital microfluidic systems. Using real-life bioassays as examples, they offer a comprehensive set of practical methodologies and tools for chip design and manufacture.
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Biotechnology
Biomedical Engineering
Circuits & Devices
Reference

Bringing together many landmark papers on the field, this compendium covers the techniques and applications of optical tweezers. It covers Arthur Ashkin’s initial work on radiation pressure and the immediate progress following his seminal demonstration. The expert contributors explore recent biological, colloidal, and microfluidic applications. They also analyze the mechanisms underpinning basic tweezer force and the interaction among many particles held within multiple tweezer systems. In addition, they explain the conversion of optical tweezers into optical spanners as well as the creation of holographic tweezers using spatial light modulators.
• Series in Optics and Optoelectronics
Molecular Biology
Optics & optoelectronics
Systems Biology
Reference
Professional

Filling a gap in current Bayesian theory, this book presents a unified Bayesian treatment of parameter inference and model comparisons that can be used with simple diffuse prior specifications. This novel approach provides new solutions to difficult model comparison problems and offers direct Bayesian counterparts of frequentist t -tests and other standard statistical methods for hypothesis testing. The book discusses nonparametric Bayesian survey analysis, gives alternatives to current frequentist nonparametric methods, and includes new goodness-of-fit methods for assessing parametric models. It also covers normal regression, analysis of variance, two-level variance component models, and finite mixtures.
• Chapman & Hall/CRC Monographs on Statistics & Applied Probability
Statistical Theory & Methods
Statistics & Computing
Reference
Professional

Starting with simple semiclassical approaches and ending with the description of complex fully quantum-mechanical methods, this book provides a complete overview of essential techniques and methods for analyzing transport in semiconductor devices. The first part examines semiclassical transport methods and provides details regarding numerical implementation and sample code as templates for sophisticated simulation software. The second part introduces the density gradient method, quantum hydrodynamics, and the concept of effective potentials used to account for quantum-mechanical space quantization effects in particle-based simulators. Numerous problems and examples supply readers with the understanding required to create their own simulators.
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Circuits & Devices
Condensed Matter Physics
Nanoscience & Nanotechnology
Textbook
Undergraduate

Largely self-contained, this text covers the computational mathematics and techniques needed to simulate magnetically confined plasmas in modern magnetic fusion experiments and future magnetic fusion reactors. Along with discussing numerical stability and accuracy, the author explores many of the algorithms used today in enough depth so that readers can analyze their stability, efficiency, and scaling properties. He focuses on mathematical models where the plasma is treated as a conducting fluid, since this is the most mature plasma model and most applicable to experiments. The book also emphasizes toroidal confinement geometries, particularly the tokamak.
• Chapman & Hall/CRC Computational Science
Computation
Computational Physics
Plasma Physics
Reference

During the last several decades, intense study has taken place on the effects of electromagnetic fields on living tissues. Reflecting this inquiry, this book discusses the theoretical and experimental evidence of these electromagnetic fields and electric pulses and examines their importance in medicine and biology. The authors present the basic techniques applied in electroporation and the advanced methods for creation of nanopores, highlighting their basic science and clinical applications. Topics include nano electroporation, classic electroporaiton, experimental evidence for electroporation of living cells, and electroporation for cancer and wound healing.
• Biological Effects of Electromagnetics
Biomedical Engineering
Electromagnetics & Microwaves
Systems Biology
Reference

It is essential for modern students of molecular behavior to understand the statistical/chemical physics at the heart of modern molecular science. But traditional presentations of this material are often difficult to penetrate. This volume brings "down to earth" some of the most intimidating but important theories of molecular biophysics. Students build understanding by focusing on topics such as probability theory, low-dimensional models, and the simplest molecular systems. The book’s accessible development of equilibrium and dynamical statistical physics makes this a valuable text for students with limited physics and chemistry backgrounds.
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Systems Biology
Bioinformatics
Statistics for the Biological Sciences
Textbook
Undergraduate

Building on the success of its popular predecessor, this second edition presents new findings on the species that are important environmental indicators. It covers nearly twice as many topics, including recent developments in the ecotoxicology of amphibians and reptiles, the current status of these animals, and intrinsic factors that affect their susceptibility to contaminants. The book also includes information on specific groups of contaminants and their effects and body burdens in herpetafauna, how contaminants interact with other ecological factors, and concerns for the future.
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Environmental & Ecological Toxicology
Marine & Aquatic Science
Reference
Professional

• Textile Progress
Industrial Textiles
Reference

While continuing to focus on common mathematical approaches to model credit portfolios, this second edition presents updates on model developments that have occurred since the publication of the best-selling first edition. It contains a new section on multi-period models and discusses recent developments in structured credit. Along with many worked out examples and numerical results, this edition also includes an expanded section on techniques for the generation of loss distributions as well as discussions of new topics, such as spectral risk measures, an axiomatic approach to capital allocation, and nonhomogeneous Markov chains.
• Chapman & Hall/CRC Financial Mathematics Series
Statistics
Finance
Financial Mathematics
Reference
Undergraduate