3D Cell-Based Biosensors in Drug Discovery Programs 'Microtissue Engineering for High Throughput SCRC Press Fecha de publicación: 30/06/2010 Páginas: 404
Formato: Hardback 235 x 156 mm
This book is based upon cutting-edge research conducted in the author’s lab (Cellular Bioengineering), which over the past decade has developed a number of sophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information.